Searchable abstracts of presentations at key conferences in endocrinology

ea0077p61 | Metabolism, Obesity and Diabetes | SFEBES2021

The Effect of Bariatric Surgery on the proteome of people achieving remission of Type 2 Diabetes

Iqbal Zohaib , Fachim Helene , Gibson John , Baricevic-Jones Ivona , Campbell Amy , Geary Bethany , Donn Rachelle , Hamarashid Dashne , Syed Akheel , Whetton Anthony , Soran Handrean , Heald Adrian

Background: Bariatric surgery (BS) results in metabolic pathway recalibration. When major metabolic change occurs, blood protein components have a key role and can be altered significantly. We set out to identify potential biomarkers of change in plasma following BS in people achieving remission of type 2 diabetes mellitus (T2DM).Methods: Longitudinal analysis was performed on serum samples from 10 individuals who all achieved remission of T2DM following...

ea0077op6.2 | Endocrine Cancer and Late Effects | SFEBES2021

The evaluation of a musculoskeletal health package intervention to prevent bone toxicity in women with gynaecological malignancies undergoing pelvic radiotherapy. The RadBone randomised controlled feasibility study

Grigoriadou Victoria Chatzimavridou , Barraclough Lisa , Baricevic-Jones Ivona , Bristow Robert , Eden Martin , Haslett Kate , Johnson Karen , Kochhar Rohit , Merchant Zoe , Moore John , O’Connell Sarah , Taylor Sally , Westwood Thomas , Whetton Anthony , Yorke Janelle , Higham Claire E

Background: Bone toxicity and more specifically Radiotherapy Related Insufficiency Fractures (RRIFs) are common late effects of pelvic radiotherapy, associated with increased morbidity and reduced quality of life, while their cost to the health system is currently unknown. The mechanisms underlying RRIFs are not well understood. Effective preventive techniques and management pathways need to be developed and validated with robust clinical and health economic analyses. The RadB...